Saarthak Sarup

Computational Neuroscience · Neuromorphic Computing

I study the architecture of neural circuits. I also paint.
Both are attempts to understand structure.

Selected Work

Synaptic Clustering in Mouse Visual Cortex

Synaptic Clustering in Mouse Visual Cortex

Paper

Discovered universal synaptic clustering patterns across petabyte-scale connectome datasets, revealing ensemble-specific wiring that challenges classical models of dendritic integration.

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Connectomics MCP Server

Connectomics MCP Server

Tool Open Source

An open-source library wrapping neuPrint, MICrONS, and FlyWire behind the Model Context Protocol, enabling LLM agents to query connectomic databases in natural language.

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Brian2 Models MCP Server

Brian2 Models MCP Server

Tool Open Source

An open-source library exposing a searchable catalog of Brian2 neural simulation models via the Model Context Protocol, enabling LLM agents to find, retrieve, and adapt published simulation code in natural language.

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Analyzing Axodendritic Motifs in Petabyte-Scale Connectomes

Analyzing Axodendritic Motifs in Petabyte-Scale Connectomes

Algorithm

Developed efficient hypergraph mining algorithms that reduced complexity from quadratic to log-linear, enabling motif discovery at scale across the largest available connectome reconstructions.

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Field Guide for Parks

Field Guide for Parks

App React Native

An offline and local AI-powered nature guide for national parks. Runs a multimodal model entirely on-device to identify plants, animals, and geological features without cell service.

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Art

A small collection of paintings — mostly acrylics and oil — made between lab hours and late nights.